Updated September 2011

Grants Awarded for the 2011-2012 Award Year

Contribution of myeloid cells to bevacizumab evasion
in glioblastoma
Manish Aghi
Department of Neurological Surgery, UC San Francisco

Dysregulated pHi and adaptive behaviors of
cancer cells
Diane Barber
Department of Cell and Tissue Biology, UC San Francisco

Using the novel cytokine IL-17D to
stimulate immune responses to cancer
Jack Bui
Department of Pathology, UC San Diego

Sema3E-mediated epithelial-to-mesenchymal-
transition in ovarian cancer
Hwai-Jong Cheng
Center for Neuroscience, UC Davis

Novel enzymatic capture methods for
the ultrasensitive microarray detection
of microRNA
Robert Corn
Department of Chemistry, UC Irvine

Influence of SRC signaling on
human pancreatic cancer progression
Timothy Donahue
Department of Surgery, UC Los Angeles

Ligand-mediated tumor supression by a neuropeptide
Brian Eliceiri
Department of Surgery, UC San Diego

Modeling oncolytic adenovirus
Hung Fan
Department of Molecular Biology and Biochemistry,
UC Irvine

Antigen-specific immunity induced by
CTLA4 blockade in melanoma
Lawrence Fong
Department of Medicine, UC San Francisco

Regulation of hematopoietic stem cell function by
the axon guidance cue Slit2
Camilla Forsberg
Department of Biomolecular Engineering,
UC Santa Cruz

Inheritance of copy number variation in the
acquisition of genomic instability
Jennifer Fung
Department of Obstetrics, Gynecology and
Reproductive Science, UC San Francisco

The Role of Wnt5a/Ror2 signaling in
mammary stem cell renewal
Lindsay Hinck
Department of Molecular, Cell and
Developmental Biology, UC Santa Cruz

Enantioenriched di- and triarylmethanes as
anticancer agents for prostate cancer
Elizabeth Jarvo
Department of Chemistry, UC Irvine

Roles of Rab21 in membrane regulation of
autophagy and cellular homeostasis
Amy Kiger
Section of Cell and Developmental Biology,
UC San Diego

Regulation of p53 in aging and cancer
Reuben Kim
Division of Restorative Dentistry, UC Los Angeles

Tumor hypoxia regulates HER3 expression
and functionc
Randall Kramer
Department of Cell and Tissue Biology,
UC San Francisco

Impact of glucuronic acid substitution on the
chemistry of heparin-derived oligosaccharides
Cynthia Larive
Department of Chemistry, UC Riverside

Anti-cancer and cytotoxic activity of
ß-amino allenes
Catharine Larsen
Department of Chemistry, UC Riverside

Targeting p25 to tumors;
A novel cancer therapeutic strategy
John Lew
Department of Molecular, Cellular and
Developmental Biology, UC Santa Barbara

Defining the mechanistic link between AR-dependent
gene regulation and cell proliferation
Maria Mudryj
Department of Microbiology and Immunology, UC Davis

Monitoring response to cancer therapy based on
imaging changes in metabolic activity
Nitin Nitin
Department of Biomedical Engineering, UC Davis

Determinants of disseminated infection in a
neutropenic mouse model of gastrointestinal
Candida albicans
Suzanne Noble
Department of Medicine, UC San Francisco

Virus-induced genomic instability in
Merkel cell carcinoma
Dennis Oh
Department of Dermatology, UC San Francisco

Systemic modulation of stem cell behavior by
the TOR signaling pathway
Nestor Oviedo
Program in Biological Sciences, UC Merced

Dissection of the role of the long non-coding
RNA Scirocco in cancerous cell proliferation
Frank Sauer
Department of Biochemistry, UC Riverside

Charting gene survival networks in
glioblastoma multiforme
Desmond Smith
Department of Molecular and Medical Pharmacology,
UC Los Angeles

Targeting pericentriolar matrix cohesion in
cancer treatment
Jorge Torres
Department of Chemistry and Biochemistry,
UC Los Angeles

Synthesis of cytotoxic polyhalogenated monoterpenes
and analogs, and evaluation of their selectivity
for solid tumors
Christopher Vanderwal
Department of Chemistry, UC Irvine

CTP synthase polymerization: a novel mechanism for
regulating nucleotide metabolism
James Wilhelm
Section of Cell and Developmental Biology,
UC San Diego

Examining the role of Fe-S cluster biogenesis in
the assembly of DNA repair complexes
James Wohlschlegel
Department of Biological Chemistry, UC Los Angeles

Discovery of redox-regulated cancer-related signaling
pathways through a screen of the S. cerevisiae
TAP-fusion library
Matthew Wood
Department of Environmental Toxicology, UC Davis

Characterization of shelterin protein TIN2 in
telomerase regulation
Lifeng Xu
Department of Microbiology, UC Davis

Regulation of nonsense-mediated mRNA decay
Alan Zahler
Department of Molecular, Cell and
Developmental Biology, UC Santa Cruz

Regulation of the class III phosphatidylinositol
3-kinase in autophagic cell death
Qing Zhong
Department of Molecular and Cell Biology, UC Berkeley

One-step miRNA analysis for study of cancer development
Wenwan Zhong
Department of Chemistry, UC Riverside

Weaponizing human EGF-containing fibulin-like
extracellular matrix protein 1 to treat
malignant gliomas
Yi-Hong Zhou
Department of Neurological Surgery, UC Irvine